How does this medication work? What will it do for me?
Omeprazole belongs to the family of medications called proton pump inhibitors (PPIs). It slows or prevents the production of acid within the stomach.
It is used to treat conditions where reduction in acid secretion is required for proper healing, including stomach and intestinal ulcers (gastric and duodenal ulcers), the prevention and treatment of ulcers associated with medications known as NSAIDs, reflux esophagitis, Zollinger-Ellison syndrome, heartburn, and gastroesophageal reflux disease (GERD).
It is also used in combination with antibiotics to treat stomach ulcers caused by H. pylori bacteria.
Your doctor may have suggested this medication for conditions other than those listed in these drug information articles. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.
Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.
How should I use this medication?
The usual recommended dose of omeprazole is 10 mg to 40 mg once daily. The dose and length of treatment depends on the condition being treated. This medication can be taken with or without food.
When used to treat stomach ulcers caused by H. pylori in adults, the dose of omeprazole is 20 mg twice daily taken with amoxicillin 1,000 mg twice daily and clarithromycin 500 mg twice daily, all for 7 days. Another dosing regimen for H. pylori infections is omeprazole 20 mg, metronidazole 500 mg, and clarithromycin 250 mg, all twice daily for 7 days.
Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.
It is important to take this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are not sure what to do after missing a dose, contact your doctor or pharmacist for advice.
Store this medication at room temperature, protect it from moisture, and keep it out of the reach of children.
This medication is available under multiple brand names and/or in several different forms. Any specific brand name of this medication may not be available in all of the forms listed here. The forms available for the specific brand you have searched are listed under "What form(s) does this medication come in?"
Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.What form(s) does this medication come in?
Each dark pink opaque cap and dark pink opaque body, hard-shell gelatin capsule, filled with white to off-white beads, axially printed with "MYLAN" over "OM 10" in black ink on both the cap and the body, contains omeprazole 10 mg. Nonmedicinal ingredients: gelatin, hydroxypropylmethyl cellulose (hypromellose 2910), methacrylic acid copolymer dispersion (Eudragit L 30 D), FDA/E172 red iron oxide, sugar spheres, Surelease E-7-7050 (ethyl cellulose aqueous dispersion; solids consists of ethylcellulose, dibutyl sebacate, oleic acid, fumed silica, and ammonium hydroxide), talc, titanium dioxide, and triethyl citrate (Eudraflex).
Who should NOT take this medication?
Each red brown opaque cap/light pink opaque body, hard-shell gelatin capsule filled with white to off-white beads, axially printed with "MYLAN" over "OM 20" in black ink on both the cap and the body, contains omeprazole 20 mg. Nonmedicinal ingredients: gelatin, hydroxypropylmethyl cellulose (hypromellose 2910), methacrylic acid copolymer dispersion (Eudragit L 30 D), FDA/E172 red iron oxide, sugar spheres, Surelease E-7-7050 (ethyl cellulose aqueous dispersion; solids consists of ethylcellulose, dibutyl sebacate, oleic acid, fumed silica, and ammonium hydroxide), talc, titanium dioxide, and triethyl citrate (Eudraflex).
Omeprazole should not be taken by anyone who is allergic to omeprazole or to any of the ingredients of the medication.
What side effects are possible with this medication?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.
The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.
Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
- abdominal or stomach pain
- diarrhea or loose stools
Although most of these side effects listed below don't happen very often, they could lead to serious problems if you do not check with your doctor or seek medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- changes in vision
- fever or chills
- flu-like symptoms
- mild skin rash or itching
- muscle aches or cramps
- pain or burning in the mouth or throat
- signs of liver damage (yellow skin or eyes, dark urine, loss of appetite, abdominal pain, fever, and fatigue)
- swelling of the hands or feet (if there is no shortness of breath)
Stop taking the medication and seek immediate medical attention if any of the following occur:
- redness, tenderness, itching, burning, or peeling of skin
- signs of an allergic reaction (e.g., difficulty breathing, hives, swelling of the face or throat)
- signs of bleeding (e.g., easy bruising, bleeding gums, nosebleeds, vomiting blood, blood in the urine, dark tarry stools)
Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.
Are there any other precautions or warnings for this medication?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
HEALTH CANADA ADVISORY
April 4, 2013
Health Canada has issued new information concerning the use of omeprazole. To read the full report, visit Health Canada's website at www.hc-sc.gc.ca.
Previous advisories on omeprazole were issued on February 16, 2012 and October 19, 2012.
To read the full Health Canada Advisory, visit Health Canada's web site at www.hc-sc.gc.ca.
Liver disease: People with severe liver disease should generally not take more than 20 mg of omeprazole daily.
Severe stomach problems: If you have recurrent vomiting, difficulty swallowing, blood in the stool, coughing up of blood, or significant unintentional weight loss, check with your doctor immediately.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, call your doctor immediately.
Breast-feeding: It is not known if omeprazole passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children.
Seniors: Using the same dosage, seniors reach higher blood levels of omeprazole than younger people. Therefore, seniors may need to take reduced doses and should generally not take more than 20 mg of omeprazole daily.What other drugs could interact with this medication?
There may be an interaction between omeprazole and any of the following:
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.
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